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Geometric changes of parotid glands caused by hydration during chemoradiotherapy
Geometric changes of parotid glands caused by hydration during chemoradiotherapy
Auteurs
Simon R. van Kranen, Sanne C. C. van Weerdenburg, Peter Remeijer, Petronella M. Kager, Olga Hamming-Vrieze, Emmy Kuipers, Wilma D. Heemsbergen en Suzanne van Beek
Abstract:
Plan adaptation during the course of (chemo)radiotherapy of H&N cancer requires repeat CT scanning to capture anatomy changes such as parotid gland shrinkage. Hydration, applied to prevent nephrotoxicity from cisplatin, could temporarily alter the hydrogen balance and hence the captured anatomy. The aim of this study was to determine geometric changes of parotid glands as function of hydration during chemoradiotherapy compared to a control group treated with radiotherapy only.